A insurance claim that the combination of Motrin and Robitussin brand medications causes heart assaults in children has no been established by reliable clinical evidence.

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Published11 February 2009

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We first received one admonition not to integrate Motrin v Robitussin via email in December 2008:

Medicine interaction!

Madison, age 8, happen away simply a few days ago. We’ve been asked to happen this on. Medical professionals told her family that there have been quite a couple of children Madison’s period that have passed away recently the same way that she did. The only common link between them was that they were given Motrin (ibuprofen) and also Robitussin together, this resulted in a love attack.

They believe this is what occurred to them. They told her to alert everyone to this. Carry out not give children both the these medicines together. You can offer them one or the other yet not both.

When Madison collapsed she endured a heart attack and they to be able to revive her however the lose of oxygen damaged her brain and she was placed on the respirator.

After this she had four strokes prior to she passed away after gift taken turn off the respirator. Please happen this on.

The story the warning is framed upon, that an eight-year-old girl called Madison passed away from a love attack and also strokes brought about by this combination of over-the-counter drugs, was unverifiable: the account noted no information regarding Madison’s surname, wherein she lived, that her medical professionals were, where she to be treated, or also the day she died. Absent any of that information, do the efforts to identify if there actually was such a child showed a virtually impossible task.

It is possible that a child deserve to have a heart attack. For example, a news report the 2 October 2007 provided heart strikes in youngsters are a rare but under-recognized trouble that are most likely resulted in by love spasms which briefly reduced off the blood supply. It thus cannot it is in ruled the end that a child called Madison (of no known last name or address) did suffer an acute myocardial infarction. However, the in rarely instances youngsters have skilled heart attacks only proves the such events happen, no that any details drug interaction causes them.

The active ingredient in children Motrin is Ibuprofen, a nonsteroid anti-inflammatory drug reliable in relieving pain and also reducing inflammation. (Ibuprofen is additionally marketed under several various other brand names, such together Advil, Medipren, and Nuprin.) children’s Motrin Suspension very first became obtainable as a prescription product in 1989, and in 1995 it to be cleared through the Food and also Drug management for marketing as an over-the-counter product. Both those landmarks occurred only ~ the product had actually been extensively tested top top children:


Before children’s Motrin became an over-the-counter product, its security profile was supported by a landmark research involving almost 84,000 youngsters — one of the largest and also most rigorous children clinical studies ever conducted. The study extended 3 years and included 1,735 medical professionals nationwide.

Robitussin Pediatric cough is a syrup that has Dextromethorphan HBr, a cough suppressant. That is Pediatric sneeze & Cold formulation has Chlorpheniramine maleate, an antihistamine, in addition to the Dextromethorphan HBr.

We have not however turned up any kind of studies confirming heart assaults brought about by the combination of these 2 over-the-counter medications, either in kids or adults, however that is not to say children should be taking OTC cold medications. An 8 October 2008 explain by the FDA supports the referral of the customer Healthcare commodities Association that kids under the period of four should no be dosed with over-the-counter cough and also cold products. This follows its January 2008 advisory that these assets not be provided in kids under the period of 2 because of the hazard of serious and potentially life-threatening next effects.

As listed in a news report indigenous September 2007: “An FDA review of side-effect documents filed v the firm between 1969 and September 2006 discovered 54 reports of deaths in children connected with decongestant medicines made through pseudoephedrine, phenylephrine or ephedrine. It additionally found 69 reports of deaths linked with antihistamine medications containing diphenhydramine, brompheniramine or chlorpheniramine. Most of the deaths were children younger 보다 2.”

The FDA provides these medication tips to the parents and also caregivers of tiny children:

Do not give kids medications labeled just for adults.Talk to your health treatment professional, such as your physician or pharmacist, if girlfriend have any type of questions about using sneeze or cold medications in children.Choose OTC cough and cold medications with child-resistant safety and security caps, as soon as available. After each use, make certain to near the cap tightly and store the medicines out that the sight and reach of children.Check the “active ingredients” section of the “Drug Facts” label of the drugs that friend choose. This section will help you know what symptoms the energetic ingredients in the medicine are intended come treat. Cough and also cold medicines often have more than one active ingredient, such together an antihistamine, a decongestant, a sneeze suppressant, one expectorant, or a ache reliever and fever reducer.Be very careful if you space giving much more than one medication to a child. Make certain the drugs do not have the same type of active ingredients. Because that example, do not offer a child an ext than one medicine that has a decongestant. If you use two medications that have actually the exact same or comparable active ingredients, her child could be harmed by getting too much of an ingredient.Carefully monitor the directions for just how to usage the medication in the “Drug Facts” component of the label. These directions tell you just how much medication to give and also how often you can give it. If you have a question around how to usage the medicine, ask your pharmacist or various other health care professional. Overuse or misuse that these commodities can lead to serious and also potentially life-threatening next effects, such as quick heartbeat, drowsiness, breath problems, and also seizures.Only usage measuring gadgets that come v the medication or those specially produced measuring drugs. Carry out not use household spoons come measure medicines for children due to the fact that household spoons come in various sizes and are not supposed for measure medicines.Understand that making use of OTC cough and cold medicines does no cure the cold or cough. These drugs only treat her child’s symptoms, such as runny nose, congestion, fever, and aches. They do not shorten the size of time your son is sick.

In 2003, another personal account circulated through e-mail implicated children Motrin in the development of stomach ulcers in a child dosed v it. We did no encounter any subsequent reports of similar instances, and also no certain interaction precaution accuse exists because that that medicine combination.

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On 22 December 2014, children’s Medical center of Dallas addressed the recirculating rumor on Twitter:

If you’ve seen a on facebook post around Motrin and Robitussin, please read and also share this. The information in the article is not correct and also was not posted by among our employees. Us encourage caregivers to discuss any type of over-the-counter medicines with your doctor and to ask around information found on the Internet.